Mu Disembala 2021, gulu lofufuza kuchokera ku Japan lidalengeza kuti lapanga katemera wochotsa omwe amatchedwa ma cell a zombie. Maselowa akuti amawunjikana ndi ukalamba ndipo amayambitsa kuwonongeka kwa maselo omwe ali pafupi, zomwe zimayambitsa matenda okhudzana ndi ukalamba monga kuuma kwa mitsempha.
Kafukufukuyu adawonetsa kuti ma cell a zombie, omwe amadziwikanso kuti ma cell a senescent m'chipatala, komanso kuuma kwa mitsempha kunachepetsedwa m'magawo a mbewa omwe adapatsidwa katemera.
Ataphunzira za ukalamba ndi maselo okalamba kwa zaka zoposa 20, ofufuza apeza kuti maselowa amachititsa kuti atherosclerosis kapena matenda ena okhudzana ndi zaka, monga matenda a shuga. Malinga ndi ochita kafukufuku, ngati tingathe kuchotsa maselo okalamba m'thupi, tikhoza kusintha mkhalidwe wonse ndi atherosclerosis, shuga, ndi zina zotero.
Zotsatira za ntchito yofufuza zomwe gululo linachita zinaperekedwa m'nkhani yomwe inaphatikizidwa mu kope la intaneti la Nature Aging.
Senescent cell ndi maselo omwe asiya kugawikana koma sanafe kwathunthu. Potulutsa mankhwala omwe amalimbikitsa kutupa, amawononga maselo athanzi omwe ali pafupi.
"Izi ndiye zotsatira zathu zazikulu. Tapeza cholembera chapadera chomwe chimawonetsa ma cell okalamba. Ndipo katemera wathu amagwira ntchito m’njira yoti azitha kuzindikira zolemberazi ndikuchotsa maselo okalamba m’thupi lathu,” anafotokoza Tohru Minamino, pulofesa ku Juntendo University ndi m'modzi mwa akatswiri ofufuza.
Gululo linapeza puloteni yomwe imapezeka m'maselo a senescent mwa anthu ndi mbewa, ndipo adapanga katemera wa peptide pogwiritsa ntchito amino acid yomwe ili gawo la mapuloteni.
Katemerayu amayambitsa kupanga ma antibodies mkati mwa thupi, omwe amadzimangirira ku maselo a senescent ndikupangitsa kuchotsedwa kwa maselowo ndi maselo oyera amwazi omwe amamatira ku ma antibodies.
Chifukwa chakuti anthu ndi makoswe amatha kutenga matenda omwewo, kafukufukuyu poyamba adachitidwa pa mitundu yosiyanasiyana ya mbewa. Avereji ya moyo wa mbewa ndi pafupifupi zaka 2.5. Koma ndi katemerayo, anakhala ndi moyo wautali. Tsopano, cholinga chomaliza cha phunziro lawo ndi anthu. Iwo akufuna kugwiritsa ntchito luso limeneli kwa odwala.
“Anthu ndi mbewa amagwidwa ndi matenda ofanana. Koma kawirikawiri, chimodzimodzi, kafukufuku ayenera kuchitika pang'onopang'ono: choyamba pa mbewa, kenako pa nyani, ndiyeno pa anthu. Palibe chifukwa chothamangira apa. Koma tidzafika kwa anthu. ” - Minamino wotsimikizika.
Kuphatikiza pa izi, adanenanso kuti pali chizindikiritso chimodzi chokha cha maselo amthupi, koma payenera kukhala ochulukirapo. Malinga ndi pulofesayu, njira yabwino ndi yakuti wodwala aliyense akhale ndi cholembera chake chomwe chingagwiritsidwe ntchito kudziwa matenda ake enieni.
Choncho, zidzakhala zotheka kusankha katemera woyenera pa vuto lililonse. Iye anatsindika kuti ichi ndi luso lochititsa chidwi lomwe kupita patsogolo kunabweretsa, zomwe zimakupatsani chidaliro choyang'ana zam'tsogolo.
"Ndikukhulupirira kuti tatsala pang'ono kukhazikitsa katemera wa anthu. Tiyenera kuzindikira zolembera zingapo zama cell okalamba, ndipo titha kupanga katemera mosavuta. Pali kale njira zingapo zothanirana ndi khansa pogwiritsa ntchito ma antibodies ... Ndikuganiza kuti tili pafupi kwambiri," - adatero wasayansi.
Ananenanso kuti akukhulupirira kuti zimenezi zidzachitika m’zaka zisanu zotsatira. Kotero, tiyeni tiyembekezere ndikuwona zomwe zidzachitike pambuyo pake. Ngati zimenezi zitakhaladi zoona, ndiye kuti odwala ambiri padziko lapansi angapindule nazo. Komabe, pangakhalenso kuipa kwa mankhwalawa komwe chitaganya cha anthu sichiyenera kuiwala konse.
