Cov tshuaj tiv thaiv Japanese tiv thaiv kev laus yuav txuas ntxiv lub neej!

Thaum Lub Kaum Ob Hlis 2021, pab pawg tshawb fawb los ntawm Nyij Pooj tau tshaj tawm tias nws tau tsim cov tshuaj tiv thaiv kom tshem tawm cov hu ua zombie hlwb. Cov hlwb no tau hais tias muaj hnub nyoog thiab ua rau muaj kev puas tsuaj rau cov hlwb uas nyob ze, ua rau muaj hnub nyoog txog cov kab mob xws li arterial stiffening.

Juntendo University
Juntendo University, Bunkyo, Tokyo. © Duab Credit: Kakidai (CC BY-SA 4.0)

Txoj kev tshawb no tau pom tias cov hlwb zombie, tseem hu ua senescent hlwb hauv kev kho mob, thiab cov hlab ntsha tawv tau txo qis hauv qee cov nas uas tau txhaj tshuaj tiv thaiv.

Tom qab kawm txog cov txheej txheem kev laus thiab kev laus ntawm cov hlwb rau ntau tshaj 20 xyoo, cov kws tshawb fawb tau pom tias cov hlwb no ua rau atherosclerosis lossis lwm yam kab mob cuam tshuam nrog lub hnub nyoog, xws li ntshav qab zib. Raws li cov kws tshawb fawb, yog tias peb tuaj yeem tshem tawm cov laus ntawm lub cev, peb tuaj yeem txhim kho tag nrho cov xwm txheej nrog atherosclerosis, ntshav qab zib, thiab lwm yam.

Qhov kev tshawb pom ntawm cov haujlwm tshawb fawb tau ua los ntawm pab pawg tau nthuav tawm hauv ib tsab xov xwm uas tau suav nrog hauv online tsab ntawm phau ntawv journal Nature Aging.

Cov hlwb senescent yog cov hlwb uas tau tso tseg tab sis tsis tau tuag tag. Los ntawm kev tso cov tshuaj uas txhawb kev mob, lawv ua rau cov hlwb noj qab haus huv uas nyob ze.

“Qhov no yog peb qhov txiaj ntsig tseem ceeb. Peb tau pom ib lub cim tshwj xeeb uas qhia txog kev laus ntawm cov hlwb. Thiab peb cov tshuaj tiv thaiv ua haujlwm zoo li nws pom cov cim no thiab tshem tawm cov hlwb laus ntawm peb lub cev, " piav Tohru Minamino, tus xibfwb ntawm Juntendo University thiab ib qho ntawm cov thawj coj tshawb fawb.

Cov pab pawg tau tshawb pom cov protein uas muaj nyob hauv cov hlwb senescent hauv tib neeg thiab nas, thiab tom qab ntawd lawv tau tsim cov tshuaj tiv thaiv peptide raws li cov amino acid uas yog ib feem ntawm cov protein.

Cov tshuaj tiv thaiv yuav siv tau los kho cov hlab ntsha, ntshav qab zib thiab lwm yam kab mob uas muaj feem cuam tshuam txog kev laus.
Cov tshuaj tiv thaiv yuav siv tau los kho cov hlab ntsha, ntshav qab zib thiab lwm yam kab mob uas cuam tshuam txog kev laus.© Image Credit: Asian Development Bank / Flickr (CC BY-NC 2.0)

Cov tshuaj tiv thaiv ua rau tsim cov tshuaj tiv thaiv kab mob hauv lub cev, uas tom qab ntawd txuas lawv tus kheej mus rau cov hlwb senescent thiab ua rau tshem tawm cov hlwb los ntawm cov qe ntshav dawb uas khi rau cov tshuaj tiv thaiv.

Vim yog qhov tseeb tias tib neeg thiab cov nas yog raug rau tib cov kab mob, kev tshawb fawb tau pib ua rau ntau hom nas. Qhov nruab nrab lifespan ntawm nas yog kwv yees li 2.5 xyoo. Tab sis nrog cov tshuaj tiv thaiv, lawv nyob ntev dua. Tam sim no, lub hom phiaj kawg ntawm lawv txoj kev kawm yog tib neeg. Lawv xav siv cov cuab yeej no rau cov neeg mob.

“Tib neeg thiab nas raug rau tib yam kab mob. Tab sis feem ntau, tag nrho tib yam, kev tshawb fawb yuav tsum tau maj mam: thawj zaug ntawm nas, tom qab ntawm liab, thiab tom qab ntawd rau tib neeg. Tsis tas yuav maj nrawm ntawm no. Tab sis peb yeej yuav tau txais rau tib neeg. " - Minamino assured.

Ntxiv rau qhov no, nws tau hais tias tam sim no tsuas muaj ib qho kev paub ntawm cov hlwb senescent, tab sis hais tias yuav tsum muaj ntau ntawm lawv. Raws li tus kws tshaj lij, qhov xwm txheej zoo tshaj plaws yog rau txhua tus neeg mob kom muaj lawv tus kheej cov cim tshwj xeeb uas tuaj yeem siv los kuaj xyuas lawv qhov mob tshwj xeeb.

Tohru Minamino, Thawj Tswj Hwm ntawm Lub Tsev Haujlwm Saib Xyuas Kev Mob Ntshav Qab Zib thiab Tshuaj Kho Mob ntawm Lub Tsev Kawm Ntawv Qib Siab Tshuaj ntawm Juntendo University.
Tohru Minamino, Thawj Tswj Hwm ntawm Lub Tsev Haujlwm Saib Xyuas Kev Mob Ntshav Qab Zib thiab Tshuaj Kho Mob ntawm Lub Tsev Kawm Ntawv Qib Siab Tshuaj ntawm Juntendo University. © Juntendo University

Yog li ntawd, nws yuav muaj peev xwm xaiv cov tshuaj tiv thaiv tsim nyog rau txhua tus neeg mob. Nws hais ntxiv tias qhov no yog qhov kev hloov pauv tshiab uas qhov kev vam meej tau coj los, uas ua rau koj muaj kev ntseeg siab los saib rau yav tom ntej.

"Kuv ntseeg tias peb nyob ze heev rau kev tsim tshuaj tiv thaiv rau tib neeg. Peb yuav tsum txheeb xyuas ob peb lub cim ntxiv rau cov hlwb laus, thiab peb tuaj yeem tsim cov tshuaj tiv thaiv yooj yim. Muaj tsawg kawg yog ob peb txoj hauv kev los tawm tsam mob qog noj ntshav siv cov tshuaj tiv thaiv ... Kuv xav tias peb nyob ze heev, " - hais tias tus kws tshawb fawb.

Nws kuj tau qhia nws qhov kev cia siab tias qhov no yuav dhau los ua qhov tseeb hauv tsib xyoos tom ntej. Yog li, cia peb cia siab thiab saib seb yuav muaj dab tsi tshwm sim tom ntej. Yog tias qhov no tshwm sim tiag tiag, ntau tus neeg mob hauv ntiaj teb yuav tau txais txiaj ntsig los ntawm nws. Txawm li cas los xij, yuav muaj qee qhov tsis zoo ntawm qhov kev kho no ib yam nkaus uas tib neeg lub neej yuav tsum tsis txhob hnov ​​​​qab.